Evidence for heterodimers of 2,4,5-trichlorophenol on planar lipid layers. A FTIR-ATR investigation.

Effects of Phenol, Catechol, Chloro- and Metylphenol on Human Erythrocyte Membrane (in vitro)

This study continues our investigations concerning the interaction of phenol, catechol, 2,4-dichlorophenol (2,4-DCP), 2,4,5-trichlorophenol (2,4,5-TCP) and 2,4-dimethylphenol (2,4-DMP) with human erythrocytes. We focus on the effects of these compounds on erythrocyte membrane fluidity, as well as on their impact on membrane proteins. The fluorimetric method and fluorescent probes (ANS, DPH and ...

Talc did not induce dominant lethal mutations or chromosomal aberrations in bone- marrow cells of rats treated in vivo, or chromosomal aberrations in human cells in vitro. Talc was not mutagenic to yeast or to bacteria in a host-mediated assay3

A. Evidence for carcinogenicity to humans (inadequate) The epidemiological studies and case reports considered with regard to producers and users of 2,4,5-trichlorophenol and 2,4,5-trichlorophenoxyacetic acid (2,4,5T) (see also summaries on chlorophenols and chlorophenoxy herbicides, pp. 154 and 156) also relate to TCDD exposure, since those products may contain TCDD as an impurity. Only studie...

Life-cycle effects of sediment-associated 2,4,5-trichlorophenol on two groups of the midge Chironomus riparius with different exposure histories.

Effects of 2,4,5-trichlorophenol (TCP) on life-cycle traits of the midge Chironomus riparius and the ability of the midge to evolve tolerance to TCP were assessed using a reference group and a group preexposed to TCP during three generations, both originating from the same laboratory culture. F1 larvae of these groups were then exposed to nominal TCP concentrations of 51, 177, 355, and 532 micr...

Purification and characterization of chlorophenol 4-monooxygenase from Burkholderia cepacia AC1100.

Burkholderia (formerly Pseudomonas) cepacia AC1100 mineralizes the herbicide 2,4,5-trichlorophenoxyacetate (2,4,5-T), and the first intermediate of 2,4,5-T degradation is 2,4,5-trichlorophenol. Chlorophenol 4-monooxygenase activity responsible for 2,4,5-trichlorophenol degradation was detected in the cell extract. The enzyme consisted of two components separated during purification, and both we...

Investigations for genotoxic effects after exposure to crude 2,4,5-trichlorophenol.